diff --git a/src/libcamera/pipeline/simple/simple.cpp b/src/libcamera/pipeline/simple/simple.cpp
index 02a98f594..b293a13e8 100644
--- a/src/libcamera/pipeline/simple/simple.cpp
+++ b/src/libcamera/pipeline/simple/simple.cpp
@@ -1427,6 +1427,11 @@ SimplePipelineHandler::generateConfiguration(Camera *camera, Span<const StreamRo
 			}
 			rawRequested = true;
 		} else {
+			if (swIspEnabled_ && processedRequested) {
+				LOG(SimplePipeline, Error)
+					<< "Software ISP can't capture multiple processed streams";
+				return nullptr;
+			}
 			processedRequested = true;
 		}